A depleted Oaklands Wolves side found high-flying Caledonia Gladiators too strong as they went down 91-60 in the WBBL.
Coach Lee Ryan was already without Julia Koppl and Miriam Carrasco-Menendez but then lost centre Amy West with a head injury when she collided with a team-mate in the warm-up.
The disruption caused by the loss of West just minutes before tip-off was clear to see as a disastrous opening period saw Wolves trail 21-7 the first break.
But to their credit, on a weekend when Cardiff scored just 19 in a 76-point loss against London and Nottingham lost by 53 at home, Wolves got their offence moving in the second period as a Jorjah Smith triple helped them cut the deficit to 46-23 at half-time.
Five straight Shaq Wade points sent Wolves into the final break trailing 68-42 as they slowed the Scottish side down, while the fourth period saw triples from Caterion Thompson and academy captain Caitlin Ryan before Gladiators wrapped up the win.
Thompson led Wolves scoring with 17 points, adding six rebounds, with Wade finishing with 15 points, eight boards and six assists. Captain Allison Day added ten points with Smith adding eight.
Wolves' two-year stay in NBL Division Two come to an end with a 111-43 home loss against unbeaten league leaders Solent Kestrels.
Faith Karahan's side stayed in touch with a Solent side, who controversially dropped out of Division One after winning four league titles in five years, during the early stages as they went into the first break trailing 29-17.
But a 16-0 run in the second quarter ended the game as a contest as Kestrels led 64-24 at half-time before outscoring the hosts 26-9 and 23-10 in the final two quarters.
Spencer Matthews led Wolves with 11 points and three assists with Oliver Rudzinski and Ethan Downing each scoring seven points, and the former adding five rebounds.
Wolves travel to Cobham Scorchers on Sunday, and have three league games remaining before joining a revamped and slimmed down Division Three next season.
Wolves academy team's hopes of a play-off spot in WNBL Division Two took a knock as they lost a key game 65-49 at East London Phoenix.
Joanna Akpan sent the visitors into the first break with a 13-12 lead but a 19-8 second period put the hosts in charge with a 31-21 half-time lead.
Oaklands did most of the scoring at the foul line as they trimmed the lead to 46-39 at the final break before the hosts finished strongly to wrap up the victory.
Caitlin Ryan led the visitors with and 11-point, 10 rebound double-double, while Amye Swinney added 10 points and seven boards, and Sarah Adepoju hit three triples on the way to nine points.
Finally, a combined 45 points from Bill Irvine (23) and Dan Kosadinov (22) couldn't prevent Wolves II going down 100-63 at Chelmsford Charge.
The hosts extended a 29-17 first period lead to 49-33 at half-time before wrapping up the win with 26-12 and 25-18 third and fourth quarters.
Wolves U14 boys reached the NBL Premier play-offs without bouncing a ball over the weekend.
For the second time this season Barking RDF failed to raise a team to face Ibrahim Gariba's side, giving them a 20-0 victory, and with other results going their way the Wolves sealed their place in the post-season.
Things were a lot tougher for the other junior Wolves in action in a weekend that saw just two home games.
The U12 girls failed to repeat their home victory against Richmond Knights as the hosts broke open a tied game in the fourth period to win 61-57 on Sunday lunchtime.
Rose Marsh led the way with 21 points as Wolves overcame a 20-13 first period deficit to outscore the hosts 10-9 in the second quarter and 20-14 in the third to set up a grandstand finish.
Evie Garvin added 10 points for the visitors.
Marsh was also in good scoring for a severely depleted U14 team as she finished with 11 on her debut in a 96-25 loss at Sussex Storm on Saturday.
Under acting coach Gariba, Wolves never recovered from a 26-7 first period. Dominique Somer added eight points
The U15 boys put a battling performance against high-flying Milton Keynes Breakers before going down 84-62 on Sunday afternoon.
Wolves trailed 23-13 at the first break and were 47-31 down at half-time but they shared 38 third period points before being outscored 18-12 in the final frames.
Two of coach La'Quarne Sayers' younger players led the way as U14 centre Sam McCree had a 16-point, 14-rebound double-double while Year 8 player Jacob Edrupt had 15 points, seven assists and three boards.
Seth Coetzee and Kean Berba both finished with nine points, with the former having the same number of rebounds and three assists.
It was a weekend to forget for the U16 boys as a pair of contrasting defeats saw their relegation fears deepen.
A poor shooting performance saw they lost 62-43 at Greenhouse Sports while they were outclassed 118-32 by London Thunder.
After trailing 17-12 at the first break on Saturday and 30-20 at half-time, Wolves fought their way back into the game with a 15-14 third period but that was as good as it got for the visitors.
The following day it was all over a 36-2 first quarter from Thunder.
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